Wounds that do not heal within 3 months are often considered as 'Chronic Wound'.
Chronic wounds seem to be detained in one or more of the phases of wound healing.For example, chronic wounds often remain in the inflammatory stage for too long. To overcome that stage and jump-start the healing process a number of factors need to be addressed such as bacterial burden, necrotic tissue, and moisture balance of the whole wound.
Chronic wounds may never heal or may take years to do so. These wounds cause patients severe emotional and physical stress and create a significant financial burden on patients and the whole healthcare system.
Most therapists may use topical antibiotics, which kill bacteria and can also help by keeping the wound environment moist, which is important for speeding the healing of chronic wounds. Some researchers have experimented with the use of tea tree oil, an antibacterial agent which also has anti-inflammatory effects.
The ideal methods of pain relief for wound patients are modalities that are topical, lack systemic side effects, noninvasive (not requiring the introduction of instruments into the body), self-administered, and display rapid onset of analgesia.
Extracts derived from the cannabis plant have been applied to wounds and other dermatological problem for thousands of years...
Stydies on Cannabis and Chronic Wounds...
-In a study published November 01, 2017, in the Journal of Pain and Symptom Managment, patients reported consistently experiencing the onset of analgesia within 3-5 minutes of each application. After the initiation of treatment with Topical Medical Cannabis, there was a statistically significant decrease in the average daily pain score and all cases demonstrated “clinically significant” pain reductions of greater than 30% which is the generally accepted threshold quoted in international pain research.
-In another study published in October 07, 2016, in the Journal of Pain and Symptom Managment, in researchers reported that before the use of Topical Medical Cannabis oil, the patient's wound was growing rapidly. Yet, after a few weeks, a modest regression of his malignant wound was observed while the patient used topical MC. This secondary outcome suggests that Topical Medical Cannabis may promote antineoplastic activity...
In summary, this is the first case report to demonstrate the potential for Medical Cannabis to provide effective pain and symptom management in the setting of malignant wounds. The rapid onset of analgesia after topical placement suggests that the effects were mediated through absorption of the THC and CBD cannabinoids that subsequently interacted with peripheral nociceptors, immune cells, and cancer cells.
-Also in a study published in July 31, 2020, in onlinelibrary.wiley.com researchers concluded that Topical Cannabis-Based Medicines, represent a promising novel, non-invasive, and safe treatment option in very challenging wounds such as NUC leg ulcers.
The ease and simplicity of its application also allows for potential self-application and selftitration by patients.Given that TCBM demonstrated
both rapid wound closure and relief of wound-related
pain.
-Finnaly it's good to mention that in the TodaysWoundClinic.com the authors suggest that Cannabis-based medicine extends the possibility for improved pain relief, safer methods with less harm and fewer iatrogenic risks, self-titration and the reinstatement of personal agency, and enhanced wound healing.
The use of cannabis-based medicine in a creative manner can improve overall relief of wound-related pain, improved quality of life, and reduce burdens and harm to patient and society.
Conclusion...
While these data are limited in their application, they add to the growing data on the effectiveness of topical cannabis for skin conditions.As with most cannabis research, we need larger clinical trials before making definitive conclusions. But this is a promising start that can provide some hope for chronic wounds patients.
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