CBD & Yoga "A Perfect Combination"

Yoga’s mind-body-spirit connection makes it popular for men and women of all ages. It teaches us to become more present with our bodies and breathing while enhancing our physical health.

But have you ever been in the middle of a yoga class and wondered why you can’t silence your thoughts???

CBD and practicing yoga together is not a new idea. In fact, the ancient Indian sacred texts of the Vedas count cannabis as one of the 5 sacred plants.

It seems like a natural fit – because the benefits of practicing Yoga and taking CBD separately are very similar – reduced stress, lower inflammation, and increased feelings of wellbeing and when taken together, they uniquely complement each other.

Yoga has been seeing an increase in popularity for many decades now, and cannabidiol is swiftly catching up. With virtually no side effects and excellent synergy, combining the two could be what you need to take your daily exercise routine to the next level of wellness.

Arizona Supreme Court: "Maternal Use of Cannabis for Morning Sickness Doesn’t Constitute Child Neglect"

The Arizona Supreme Court has declined to hear any further challenges to an appellate court ruling which determined that child welfare officials acted inappropriately when they placed a woman on a state registry for having consumed medical cannabis while pregnant. 

The Court’s order, issued Thursday, removes the mother’s name from appearing on the state’s registry, which is accessible to employers performing background checks.

The Arizona Department of Child Safety initially took action against the mother, Lindsey Ridgell, in 2019 when her newborn tested positive for cannabis. Last April, justices on the Arizona Court of Appeals unanimously ruled that the prenatal exposure in this case did not constitute “neglect” because the mother was medically authorized under the law to consume cannabis products to treat symptoms of morning sickness. 

"The use of Medical Cannabis for Treating Cancer Related Symptoms in Oncology Patients"

Many comorbidities are associated with oncology diseases. In cancer, the associated symptoms include pain, anxiety, depression, insomnia, decreased in quality of life, increased disability and negative effects on sexuality.

These symptoms are some of the most fundamental causes of suffering and disability for oncology patients while undergoing therapies, and some may even lead to worse prognosis.

Traditionally, cancer-related pain is mainly treated by opioid analgesics but a promising substitute for opioid-based medication is Medical Cannabis (MC) and Cannabinoid treatment for cancer-related pain is generally recognized as safe!

Despite the fact that there is a knowledge gap in the study of Cannabis, especially for treating cancer-related pain, a 2020 study showed that most cancer patients requested MC treatment from their oncologist.

The Adverse Effects (AEs) from cannabinoids for cancer treatment are generally well tolerated by the patients and categorized as mild to moderate and the most frequent AEs are memory impairment, drowsiness, nausea, vomiting and xerostomia (dry mouth).

The Study...

This long-term study was conducted between January 2019 and September 2021 in Israel and pulished in Frontiers in Pain Research on 20 May 2022.

The institutional Ethics Committee of Haemek Medical Center and Galil Medical Center also approved the study.

Researchers conducted a multi-center, prospective, 6-month longitudinal study that followed up on the effectiveness and safety parameters of MC treatment for cancer-associated symptoms.

Endocannabinoid system: Essential and mysterious

Many of us have heard of some of the transmitter systems within our bodies, such as the nervous system, which gives us our fight-or-flight response. Fewer have heard of the more recently discovered endocannabinoid system which is amazing when you consider that the ECS is critical for almost every aspect of our moment-to-moment functioning. 

The ECS regulates and controls many of our most critical bodily functions such as learning and memory, emotional processing, sleep, temperature control, pain control, inflammatory and immune responses, and eating. The ECS is currently at the center of renewed international research and drug development.

What is the ECS?

The ECS comprises a vast network of chemical signals and cellular receptors that are densely packed throughout our brains and bodies. The "cannabinoid" receptors in the brain — the CB1 receptors — outnumber many of the other receptor types on the brain. They act like traffic cops to control the levels and activity of most of the other neurotransmitters. This is how they regulate things: by immediate feedback, turning up or down the activity of whichever system needs to be adjusted, whether that is hunger, temperature, or alertness.

A second type of cannabinoid receptor, the CB2 receptor, exists mostly in our immune tissues and is critical to helping control our immune functioning, and it plays a role in modulating intestinal inflammation, contraction, and pain in inflammatory bowel conditions. CB2 receptors are particularly exciting targets of drug development because they don’t cause the high associated with cannabis that stimulating the CB1 receptors does (which is often an unwanted side effect).

To stimulate these receptors, our bodies produce molecules called endocannabinoids (also called endogenous cannabinoids), which have a structural similarity to molecules in the cannabis plant, the anandamide (AEA) & the 2-arachidonoylglyerol (2-AG)

"Neuroprotective Effects Of Cannabis" by Sensi Seed

Following on from our recent article on the relationship between cannabis use and stroke, we now investigate the role of cannabinoids in mitigating brain damage caused by traumatic brain injury and ischemic stroke. There is mounting evidence to suggest that their various properties have great therapeutic potential.

-Antioxidative & anti-inflammatory properties

In recent years the evidence for the antioxidative and anti-inflammatory properties of various cannabinoids has become well-established, and our understanding of the role they play in modulating neurotransmission too has grown. Thus, serious consideration is now being given to their potential as neuroprotective agents. Cannabinoids have been shown to prevent neuronal death in acute neuronal injury, including Ischemic Stroke (IS) and Traumatic Brain Injury (TBI), as well as provide symptomatic relief in Multiple Sclerosis (MS), Huntington’s disease, and other chronic neurodegenerative diseases.

"The Begining of Western Medicine"

Our little story begins from the Middle Ages and with two powerful and very profitable products... Opium & Oil.

In 1803 Friedrich Sertuerner  discovers an active ingredient in opium which if you dissolved in acid and then neutralizing it with ammonia result of this is... Morphine. 

Morphine was not only the first alkaloid to be extracted from opium, but the first ever alkaloid to be isolated from plant. 

In 1827 E. Merck & Company of Darmstadt, begins the commercial manufacturing of morphine for healing purposes.  It would become a dominant manufacturer of morphine, codeine and cocaine.

When we think of Bayer we think of aspirin, definitly not heroin.... but in 1895 Bayer Company of Elberfeld, finds that diluting morphine with acetyls produces a drug without the common morphine side effects and the name for this new compound... Heroin   
  
And where you find acetyls to produce heroin?  Where did the acetyls come from?  Well, just like today they come from petrochemicals, and sudenly all this led us to a name.... "John D. Rockefeller" the oil baron... 

How To Use CBD For Unbelievable Sleep

These days, it is almost impossible for people to “turn off” between constant smartphone connection and rising digital social pressures, rates of insomnia and other sleep-related disorders 

Whether you toss and turn all night, or lay there thinking about the problems of the day, it can be frustrating not getting great sleep, especially if you’ve tried all of the things that are supposed to help:

• Exercising during the day
• “Winding down” an hour before bed
• Not consuming caffeine beverages in the afternoon
• Going to bed at the same time every night, with the same routine
• Stop drinking alcohol
• Creating a super dark room with blackout shades
• Putting in ear plugs
• Turning on the blue-light filter on your phones or putting away your devices completely before bed-time
• And every vitamin, supplement, and herb out there!

The fact is, sometimes you still can’t get a good night’s sleep. It’s not your fault there’s something bigger going on.

If you don’t want to resort to prescription medications, then CBD could be the answer you’ve been waiting for. It does absolutely jaw-dropping things to your sleep because of its many wonderful medicinal properties.

It can stop the racing thoughts, help you calm down and finally get the kind of deep, restorative sleep you’ve been dreaming about for YEARS. In this mega-guide, we’re going to show you how.

"CANNABIS & SPIRITUALITY"

The stoner stereotype is a familiar one that transcends cultures...

But as legalization allows cannabis to be discussed maturely, that trope seems like a dying remnant of the decades-long smear campaign against a plant that can truly impact our lives, culture, and economy in a positive way. 

With the relaxation of Cannabis stigma, people can explore a path of spirituality, studying the plant’s use as a tool for inner exploration and enlightenment.

Much like any other psychedelic substance, cannabis can be abused and consumed without respect to its potency, power, or healing potential. Certainly, there’s no harm in using it as a tool to relax and decompress from life’s daily stresses, but some might argue there’s a point of diminishing return when consuming copious amounts without setting the right intention.

And for religions that consider the plant sacred, this is typically their view on the use of cannabis — using it heedlessly is considered a sin or frowned upon, while using it for enlightenment or spirituality is accepted, and in some cases, encouraged.

"Finally... is CBD Better Than Aspirin...?

Probably if you search on internet you will find many post's wich claims that CBD is better or stronger than Aspirin. 

And probably you are so quite sure about the safety of Aspirin, in  point that you may be laugh...

So, lets take a closer look to Aspirin and to CBD and lets see what we will find out!!!


Aspirin, also known as acetylsalicylic acid (ASA), is a medication used to treat pain, fever, or inflammation. Specific inflammatory conditions which aspirin is used to treat include Kawasaki disease, pericarditis, and rheumatic fever.Aspirin given shortly after a heart attack decreases the risk of death. Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. It may also decrease the risk of certain types of cancer, particularly colorectal cancer. 

"The most of us we dont know exactly how many adverse effects has this 'innocent' pill..."

"New compound from CBDA could be substitute for opioids & steroids"

Israeli researcher Raphael Mechoulam has announced the development of a process to modify and stabilize cannabidiolic acids (CBDA) that appear early in the cannabis plant’s growth, rendering compounds that have the potential for large-scale use.

The result is a semi-synthetic, fully stable, acid-based compound that could be useful in suppressing nausea from chemotherapy, and be a treatment for such afflictions as Inflammatory Bowel Disease (IBD) and Psoriasis. 

Researchers say such compounds, which are more potent than CBD or THC – and which so far have shown no negative side effects – could replace steroids and opioids.

Politically correct for pharma

Mechoulam worked with American biotech startup EPM to develop the solution to stabilizing the acids through esterification, a simple chemical process. That could prove interesting to the pharmaceutical industry as the process turns out the acids in a consistent form that is patentable. Also, EPM CEO Reshef Swisa said the U.S. Food and Drug Administration has told the company the compound would not be treated as cannabis but as any other drug in development, thereby avoiding the stigma and legal limitations associated with marijuana.

"New Studies Reveals That Cannabis Helps PTSD Patients"

Post-traumatic stress disorder (PTSD) is a mental disorder that can develop after a person is exposed to a traumatic event.

This debilitating condition causes chronic problems like nightmares, panic attacks, hypervigilance, detachment from others, overwhelming emotions, and self-destructive behavior.

Unfortunatelly these overwhelming symptoms can even lead to suicide.

The current method of treating PTSD is to medicate the symptoms, not to actually treat the patient. In fact, many of the medications prescribed do the opposite and suppress the brain’s natural healing functions.

Because of this, many PTSD patients are stuck in a cycle: take pills, feel sedated, stop taking pills, then feel alive until the massive hammer of symptoms comes back. This is why we see so many veterans taking their own lives – not to mention the number of first responders who are suffering and who rarely get discussed.

Many PTSD patients have been saying for years that cannabis helps with their PTSD.

 

Previous research has shown that cannabis has the potential to reduce anxiety, or even prevent heightened anxiety in threatening situations. But up to this point, no studies had investigated this response in adults dealing with trauma - such as those with PTSD. 

Two new studies point to the way that cannabinoids may help treat PTSD. One shows how cannabis can reduce activity in the amygdala (part of the brain associated with fear responses to threats) andd the other suggests that the plant’s cannabinoids could play a role in extinguishing traumatic memories. Both effects could be therapeutic for those suffering from PTSD - according to those studies.

"CBD Improves Blood Flow to Brain’s Hippocampus"

Cannabidiol (CBD) increases cerebral blood flow to areas of the brain associated with memory processing, specifically the hippocampus. The findings identify a potential mechanism for the use of CBD to treat disorders associated with altered memory processing, including Alzheimer’s disease, PTSD, and schizophrenia.

A single dose of cannabidiol (CBD) helped increase blood flow to the hippocampus, an important area of the brain associated with memory and emotion, finds a new study led by UCL researchers.

Researchers say the findings could be an important discovery for conditions which affect memory, such as Alzheimer’s disease and post-traumatic stress disorder (PTSD), and could help better target therapies.

In the study, published in the Journal of Psychopharmacology, researchers set out to investigate how CBD influences cerebral blood flow in different regions on the brain involved in memory processing.

Lead author, Dr Michael Bloomfield (UCL Psychiatry) said: “Cannabidiol is one of the main constituents of cannabis and is gaining interest for its therapeutic potential.

"Using CBD to Treat the Symptoms of Alzheimer’s & Other Forms of Dementia"

Worldwide, 50 million people are living with Alzheimer's and other dementias.

Alzheimer’s disease is a degenerative brain disease and the most common form of dementia. 

Dementia its an overall term that describes a group of symptoms.

Dementia is a general term for loss of memory, language, problem-solving and other thinking abilities that are severe enough to interfere with daily life. Alzheimer's is the most common cause of dementia.

The dementia-related conditions that can be helped by CBD include: Alzheimer’s disease, Vascular Dementia, Dementia with Lewy bodies (DLB), Parkinson’s disease, Frontotemporal dementia and Huntington’s disease.

According to researchers at California’s Salk Institute, their 2017 study has found evidence that cannabinoids such as CBD could help remove dementia from, and increase connections between, brain cells. Those results were validated by other laboratories. 

There are three ways CBD can work to improve health outcomes for persons with dementia: by reducing inflammation, by reducing oxygen buildup, and by working as a brain stimulant and neuroprotectant. From a user’s perspective, CBD may reduce stress and anxiety in the individual with dementia as well as reduce the decline of memory and other brain functions.

"Safety and efficacy of cannabidiol in children and adults with treatment resistant Lennox-Gastaut syndrome or Dravet syndrome"

Since 2014, patients with severe treatment-resistant epilepsies (TREs) have been receiving add-on cannabidiol (CBD) in an ongoing, expanded access program (EAP), which closely reflects clinical practice.

Researchers conducted an interim analysis of long-term efficacy and tolerability in patients with Lennox-Gastaut syndrome (LGS) or Dravet syndrome (DS) who received CBD treatment through December 2016.

The Study...

Children and adults with LGS/DS taking stable doses of antiepileptic drugs (AEDs) at baseline were included from 25 EAP sites across the United States.

During the 4-week baseline period, parents/caregivers kept diaries of all countable seizure types. Patients received a pharmaceutical formulation of highly purified CBD in oral solution at 2-10 mg/kg/day, titrated until tolerability limit or a maximum dose of 25-50 mg/kg/day.

"CBD and Epilepsy"

Epilepsy is a common neurologic disorder, it is estimated that ∼50 million people are affected worldwide. 

About one third of those patients are drug resistant, defined as failure to stop all seizures despite adequate trials of at least 2 appropriate medications.

CBD (cannabidiol) has been shown to be an effective treatment for epilepsy, particularly in reducing the frequency and severity of seizures in people with certain types of epilepsy.

In 2018, the FDA approved a CBD-based medication called Epidiolex for the treatment of two rare forms of childhood epilepsy, Lennox-Gastaut syndrome and Dravet syndrome. Clinical trials showed that Epidiolex significantly reduced the number of seizures in patients with these conditions.

CBD works by interacting with the body's endocannabinoid system, which plays a role in regulating various bodily functions, including mood, pain, and sleep. It is thought that CBD may help to reduce seizures by interacting with certain receptors in the brain and nervous system.

There has been an enormous interest in developing antiepileptic drugs with novel mechanisms of action. This review discusses the evidence supporting the anticonvulsant properties of cannabis in humans, focusing on cannabidiol.

"CBD could help people quit cannabis bad habit"

A benchmark clinical trial published on 28/07/2020 shows that cannabidiol (CBD) could be a safe and effective treatment for problematic cannabis use. 

Results from the first-ever randomised clinical trial of CBD for cannabis use disorder suggests that prescribed doses of the non-intoxicating constituent part of the cannabis plant could help people kick the habit.

In the MRC-funded trial, published in the Lancet Psychiatry, researchers administered doses of CBD or placebo to 82 volunteers who were motivated to quit using cannabis but had previously failed to do so. They measured the effects of the drug on levels of cannabis use both during a four-week treatment period and up to six months follow-up.

As this was the first clinical trial to assess CBD for reducing cannabis use, they tested three different doses of CBD in an adaptive design to find out which doses might be most effective.

• In the first stage of the trial, 48 volunteers received either placebo or CBD at doses of 200mg, 400mg or 800mg. The researchers found that the lowest dose of 200mg CBD was ineffective and so they dropped it from the trial.
• In the second stage of the trial, the researchers recruited an additional 34 volunteers to receive either placebo, 400mg or 800mg CBD. At the end of the trial, they found consistent evidence that CBD at 400mg or 800mg was more effective than placebo at reducing cannabis use.

"CBD and Schizophrenia Safety and Effectiveness"

Schizophrenia is a mental illness characterized by continuous or relapsing episodes of psychosis.

Major symptoms include hallucinations, delusions and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and lack of motivation.

Cannabis and mental health are strongly linked.Cannabis helps support health across various facets of mind, brain and body. But there is no end to the wellness advantages it can offer.Cannabis can assist with mental health, help clear your mind, and alleviate depression.It will help you concentrate, and open up a whole fresh realm of energy and liveliness.

The two most abundant cannabinoids in Cannabis are THC and CBD. Different forms of cannabis vary in the relative proportions of THC and CBD, and the risk of psychotic symptoms and impaired cognitive functioning following cannabis use is lower with cannabis preparations that have a relatively high CBD content.

The aim of the present study was to explore the safety and effectiveness of CBD as an adjunctive treatment in schizophrenia. Researchers examined the effects of CBD on positive and negative psychotic symptoms, cognitive performance, level of functioning, and the treating psychiatrist’s overall clinical impression.

"Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy"

There has been a dramatic increase in the number of children diagnosed with autism spectrum disorders (ASD) worldwide. 

Recently anecdotal evidence of possible therapeutic effects of cannabis products has emerged. 

The aim of this study is to characterize the epidemiology of ASD patients receiving medical cannabis treatment and to describe its safety and efficacy. 

Researchers analyse the data prospectively collected as part of the treatment program of 188 ASD patients treated with medical cannabis between 2015 and 2017. The treatment in majority of the patients was based on cannabis oil containing 30% CBD and 1.5% THC.

The Study...

During the study period, 188 ASD patients initiated the treatment. Diagnosis of ASD was established in accordance with the accepted practice in Israel. 6 board certified paediatric psychiatrists and neurologists were responsible for treatment of 125 patients (80.6%), the remaining 30 children were referred by 22 other physicians.

"CBD Vs COVID-19"

In a previeus article we had speak about cannabis terpens against Covid-19. Now we examine the first study of that article to understand better, not only, the way CBD can help us with viruses but how CBD act with our bodies for a better health.Lets say that this is another litle pice of the puzzle...

Researchers at the University of Lethbridge say while clinical trials still need to be done, data they’ve been collecting over the past four years shows promise that some cannabis extracts may help in the prevention and treatment of COVID-19.

The researchers of this study, Olga and Igor Kovalchuk have been working with cannabis since 2015, using varieties from around the world to create new hybrids and develop extracts that demonstrate certain therapeutic properties.

"When COVID-19 started, Olga had the idea to revisit our data, and see if we can utilize it for COVID.We were totally stunned at first, and then we were really happy," says Olga.

"It was like a joker card, you know, coronavirus. It just mixes up everybody’s plans," says Olga.

"CBD Oil for Peripheral Neuropathy"

Neuropathy can affect your overall wellbeing and quality of life. It involves an intense pain that is challenging to manage because it affects the nerves of the peripheral nervous system. 

Patients suffering from neuropathy often use opioids pain medications. Although these medications can be useful in reducing pain, they pose the risk of overdose, addiction, and abuse.

Due to this, most people look for alternative treatments.

CBD is becoming a preferred alternative remedy for patients with neuropathy. This is because its the non-psychoactive component of marijuana that has numerous health benefits. CBD doesn’t produce any side effects and is an appropriate option for patients.

What is Peripheral Neuropathy?

Understanding what Peripheral neuropathy means is important to appreciating the possible remedy that CBD oil brings to the victims. It is a medical disorder that occurs when there is damage to the nerves that link the other body parts such as skin and muscles to the spinal cord and the brain. Damage to these nerves interferes with communication between other parts of the body and the brain. Besides, it reduces sensation in the legs and arms, affects movement and causes pain.

However, the dose matters when it comes to neuropathic pain, and it is crucial to start with small doses and examine their impact on your body before increasing the quantity. Once you get a preferred dosage, stick to it.