Probably you have hear that cannabinoids & the endocannabinoid system play an important role in our daily lives regulating and maintaining homoeostasis in our bodies.
But did you know that actually their role is so crucial that they effect all the major stages of our lives from conception, embryo implantation, birth to the early days of our lives?
Male fertility...
Both CB1 and CB2 receptors are found on sperm cells. The level of endocannabinoid AEA is crucial for control of the percentage of swimming and live sperm (viability and motility), the modulation of the energy expenditure and control of the number of testosterone producing cells (Leydig cells).
These effects are mediated through the CB1 receptor. CB2 receptor activation is responsible for the start of the production of sperm and the regulation of its swimming speed.