Monday 4 May 2020

"Could cannabis terpene formulation treat COVID-19"?

After the Canadian University of Lethbridge, which announced a few days ago, the promising first results of its research on the possible contribution of the plant and cannabinoid derivatives in the treatment of the new virus, the Israeli company CannaSoul also announced that it is proceeding with relevant studies.

So lets see what those two studies report about Cannabis & Covid-19.

-In the first study, according to the calgary.ctvnews, researchers presented a series of data according to which components of the cannabis plant effectively contribute to inhibiting the invasion of Covid19 in the human body.

The researchers point out that further clinical studies will be needed to finalize the results of their research, but they do not hide their optimism. According to their findings, based on preliminary data and pending further investigation, high-cannabidiol-CBD cannabis anti-inflammatory extracts can regulate the action of receptors in organs such as the mouth and lungs.


One of the receptors, known as ACE2, has been shown to be one of the main gateways for the COVID-19 virus to enter the body. "The virus has the ability to bind to this receptor and enter the body through it as if it were opening a door," the researchers said. "But some of the ingredients in cannabis help slow the spread of the virus by preventing it from entering the body through ACE2."

"Imagine that our cell is like a big building full of doors," said geneticist Igor Kovalchuks, who conducted the study with his wife, biologist Olga Kovalchuk. "Cannabinoids reduce the number of doors in this building by 70%. So we're more likely to fight the virus. "

"Early discoveries show that cannabis extracts could be used against the spread of the virus in inhaled products, mouthwashes and mouthwashes both as a clinical practice and in home use," said the two Ukrainian scientists. in recent years intensively in Canada investigating the effect of cannabis ingredients on a number of diseases.

The research couple had gathered a wealth of data from their research to date on cannabinoid activity and in the midst of the pandemic, they worked to see if their data could be used against Covid19.


Novel antiviral terpene formulation...

-In the second study,according to healtheuropa.eu the cannabis terpene formulation is uniquely dedicated for the treatment and prevention of viral infections and is specifically designed for high-risk populations and treatment of infections such as the COVID-19 novel strain of coronavirus.

The novel formulation is designed to be consumed by direct inhalation.
CannaSoul Chairman, Professor Dedi Meiri of the Israel Institute of Technology, said: “Our lab has been approved to operate as a corona lab, and in doing so, we are promoting two studies based on existing cannabis studies.

First, we will try to identify the plant’s own molecules that are capable of suppressing the immune response to the COVID-19 coronavirus – which causes inflammation and severe disease – to lower the immune system response without suppressing it, thereby providing better complementary treatment to the steroids, which completely suppress the immune system.”

The researchers are looking at the ACE2 receptor – which allows the virus to inject its genetic expression into human cells and proliferate.

Meiri continued: “There is a process that examines the effect of cannabis molecules on proteins as well, and we are now examining which ones are relevant to the same receptor, with the goal of reducing its expression, making it difficult for the virus to enter the cell and proliferate.”

Eybna’s CEO, Nadav Eyal, said that: “This type of delivery method is a game-changer, enabling us to achieve therapeutic qualities from these unique phytochemicals like never before."

The Cytokine Storm Syndrome..

The studies hope to provide treatment for viral infections via modulation of ‘Cytokine Storms’. A number of COVID-19 cases have been linked to ‘Cytokine Storm Syndrome’ whereby the immune system goes into overdrive and releases too many cytokines – proteins important in cell signaling – into the body at once, attacking healthy lungs and causing massive organ failure.

The collaboration will enable CannaSoul’s analytical expertise, which is based on accumulated clinical data, and Professor Meiri’s pioneering research to customise Eybna’s novel terpene formulation for optimising its anti-inflammatory and anti-viral properties.

As for now all this are a very promising news aboyt the efect of Cannabis in viruses. So, we hope that research on the medicinal effects of the plant, which has grown dramatically in recent years, will provide usable tools in the fight against the new virus. 

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