Cannabinoid receptor problems in the placenta may cause miscarriage, according to new study.
The role that the endocannabinoid system plays in reproduction has been studied for years.
There is strong support of its involvement in maintaining the health and function of the placenta, and thus preventing miscarriage.
There is strong support of its involvement in maintaining the health and function of the placenta, and thus preventing miscarriage.
There are at least four kinds of receptors in the human body, each activated by cannabinoids. The most commonly known receptors are CB1 and CB2. The peroxisome proliferator-activated receptor-g (PPAR-g) and the G-protein coupled receptor GPR55 are additional receptors that interact with cannabinoids. Science has more recently discovered that ion channels also participate in conveying messages of cannabinoid molecules, including TRPV1 and TRPM8.
-The Placenta and Cannabinoid Receptors
The main function of the human placenta is nourishment, oxygen and carbon dioxide exchange, and protein biosynthesis for the fetus. The placenta is its own organ, consisting of many different cell types. Metabolism within the placenta creates the microenvironment necessary to support development of human life.
Scientists discovered that placental cells express cannabinoid receptors CB1 and CB2, which suggests that cannabinoids from cannabis consumption may impact placenta functioning.