"CBD & Seizures in Lennox–Gastaut syndrome"

 

Researchers provide further evidence that the cannabis compound, CBD, is effective at reducing seizures in people with epilepsy.

The new study reveals CBD significantly reduced seizures in people with Lennox-Gastaut syndrome. Previously, the researchers demonstrated CBD was effective at seizure control in Dravet syndrome.

Cannabidiol (CBD), a compound derived from the cannabis plant that does not produce a “high” and has been an increasing focus of medical research, was shown in a new large-scale, randomized, controlled trial to significantly reduce the number of dangerous seizures in patients with a severe form of epilepsy called Lennox–Gastaut syndrome.

In the new study comparing 2 doses of CBD to a placebo, the researchers reported a -41.9% reduction in “drop seizures” (a type of seizure that results in severe loss of muscle control and balance) in patients taking a 20 mg/kg/d CBD,
-a 37.2 percent reduction in those on a 10 mg/kg/d CBD and
-17.2 percent reduction in a group given a placebo.

“This new study adds rigorous evidence of cannabidiol’s effectiveness in reducing seizure burden in a severe form of epilepsy and, importantly, is the first study of its kind to offer more information on proper dosing,”
says Dr. Devinsky.

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"How to Make Cannabidiol Infused Ice Cream at Home"

Can’t wait for Half Baked Ben and Jerry’s infused Ice Cream? It’s time to whip up a batch of basic vanilla CBD ice cream at home.

A vanilla base is all you need to create a world of flavors, from berry blends to chocolate ripples, to your own Half-Baked creations.

Ingredients: 

• 2 cups heavy cream
• 1 cup whole milk
• ⅔ cup honey
• ⅛ tsp fine sea salt
• 6 large egg yolks
•  2 tsp vanilla extract
• 1/2 gram of your favorite CBD powder

Directions:

"Cannabinoids & Glioblastoma Therapy"

Glioblastoma (GBM) is the most malignant brain tumor and one of the deadliest types of solid cancer overall. More than 95% of GBM patients die within 5 years after diagnosis. Accumulating evidence indicates that cannabinoids have potent anti-tumor functions.

Glioblastoma...

Half of newly-diagnosed gliomas are glioblastomas (GBMs), with an incidence in adults of 0.59 3.69 cases per 100,000 person life-years. Primary GBM occur more commonly in male patients whereas the reverse is the case for secondary GBM. The mean age of primary and secondary G BM patients is 62 and 45 years, respectively (Adamson et al., 2009).

Cannabinoids...

The term cannabinoids originally described bioactive constituents of the plant Cannabis sativa. The cannabis ingredients were used traditionally for their medicinal purpose but also for their recreational properties. Most of the cannabinoids bind to G-protein coupled cannabinoid receptors, CB1 and CB2, and act as agonists or inverse agonists.

"Industrial Hemp,Agronomy and Ultilization"

There are increased interests in growing grain and fiber hemp (Cannabis sativa L.) as well as in large-scale hemp products. Cannabis has been grown/ utilized for thousands of years as a fiber, grain, and medicinal plant. 

However, the strict control of cannabis cultivation to combat illegal use, the spread of new yarns and oilseeds, and the advent of cheap synthetic fibers caused a decreased/eliminated hemp production

Hemp has a long history of being used for fiber, grain, and medicinal purposes, but its cultivation has been strictly controlled due to concerns about illegal drug use, competition from synthetic fibers, and bans in many countries.

However, with the legalization of hemp in the USA through the 2014 and 2018 Farm Bill, research programs have been launched by universities to explore its potential. Hemp has the advantage of being a versatile crop that can be used for multiple purposes, creating opportunities for the market to value hemp products.

This paper, published on MDPI Open Access Jurnals, highlights that hemp has the potential to be a sustainable and environmentally friendly crop, with its ability to absorb heavy metals, sequester carbon, and suppress weeds without the use of pesticides. The paper aims to examine the historical and recent literature on hemp agronomy and utilization, focusing on industrial hemp for grain and fiber production.