"True Cannabis Stories 2"

Ιf someone look at the internet he will be able to find stories about what Cannabis can do when we use it right.Here we will see 3 more stories about how cannabis actually improved  the life of 3 childrens...

-In 1993,Rebecca Sewell as a ten-year-old, she unknowingly participated in a magic trick where some handcuffs were placed on her ankle.She was injured and diagnosed with Complex Regional Pain Syndrome (CRPS) as it turns out, but after months of therapy it went into remission, until 2006.The pain she remembered as a ten-year-old came roaring back.

“I know this will irritate many chronic pain sufferers, but opioids don’t alter chronic pain, they mask it” she said, a message that she plans to share at the Illinois Cannabis Education Expo.

CANNABIS AND MASSAGE, A PERFECT MATCH?

Cannabis and massage are both techniques that have been used far back into history in order to treat conditions such as pain. Both modalities work effectively when used in isolation, however some therapists are now using them in combination and reporting powerful effects.Perhaps one of the better-known uses of medical cannabis is its effects against chronic pain. Cannabis has a similarity with massage in that its use as a medical treatment spans far back into history, having been used in China from 2700 BC and India from 1000 BC. Cannabis plants produce a resin that is loaded with chemicals known as cannabinoids. 

"True Cannabis Stories"

While the cancer industry is loath to admit it, many patients have had success in treating their cancer at home with cannabis —  after conventional therapies like chemo and radiation failed. The researchers say that their findings prove that cannabis can be used as a cancer treatment. Does that mean plants will finally start getting recognized for their medicinal powers...? 

Hormonal Imbalance: A Beginner’s Guide by Endoca

Are you amongst the slightly confused, when it comes to hormonal health? Are you still wondering how to control your hormonal imbalance? The human body produces approximately 50 different hormones all working towards helping you maintain homeostasis. Hormones are best described as chemical messengers that travel around the bloodstream instructing tissues and organs on how to do their job.

Not only are hormones vital to your health and your well-being, but their job is also irreplaceable. When you produce either too much or too little of any given hormone, you experience what we call “hormonal imbalance”.

This imbalance doesn't need to be very severe in order to cause problems, as even small fluctuations in your hormone levels can end up having serious effects on your body.

"Study Finds Miscarriage May Be Prevented By THC"

Cannabinoid receptor problems in the placenta may cause miscarriage, according to new study. 

The role that the endocannabinoid system plays in reproduction has been studied for years. 

There is strong support of its involvement in maintaining the health and function of the placenta, and thus preventing miscarriage.

There are at least four kinds of receptors in the human body, each activated by cannabinoids. The most commonly known receptors are CB1 and CB2. The peroxisome proliferator-activated receptor-g (PPAR-g) and the G-protein coupled receptor GPR55 are additional receptors that interact with cannabinoids.  Science has more recently discovered that ion channels also participate in conveying messages of cannabinoid molecules, including TRPV1 and TRPM8.

-The Placenta and Cannabinoid Receptors

The main function of the human placenta is nourishment, oxygen and carbon dioxide exchange, and protein biosynthesis for the fetus. The placenta is its own organ, consisting of many different cell types. Metabolism within the placenta creates the microenvironment necessary to support development of human life.

Scientists discovered that placental cells express cannabinoid receptors CB1 and CB2, which suggests that cannabinoids from cannabis consumption may impact placenta functioning.

"Does CBD Have Medical Benefits for Dogs"?

As with any pet wellness trend, when it comes to CBD oil for dogs, there’s a lot of information floating around online.

Of course, you want to do what’s best for your pup, which leads to the question: What do I need to know about CBD oil?

Every animal with a spinal column has an endocannabinoid system (ECS), which scientists estimate evolved more than 600 million years ago and has been carried forward across the millennia.

This ancient system—discovered through the work of several researchers between roughly 1965 and 1995—is named for Cannabis sativa L., the plant species that most dramatically affects it.

Its basic functions have been summarized as to “relax, eat, sleep, and protect.”


Ok all this, but how CBD Is Thought to Help Dogs...???

Researchers are still learning CBD’s specific effects on dogs, but here’s how the compound is thought to work:

Dogs have an endocannabinoid system (ECS), just like humans. 
The ECS is a network of cellular activators and receptors in the body that regulate physiological processes, including pain, mood, inflammation, stress, and more. 

CBD binds to and activates the vanilloid, adenosine, and serotonin receptors in a dog’s ECS and helps to regulate pain perception, inflammation, temperature, and more. It also boosts dopamine levels, helping to reduce anxiety and improve mood. 

CBD also blocks GPR55 signaling, which decreases cancer cell reproduction.

"Marijuana as Medicine" from National Institute on Drug Abuse

The term medical marijuana refers to using the whole, unprocessed marijuana plant or its basic extracts to treat symptoms of illness and other conditions. The U.S. Food and Drug Administration (FDA) has not recognized or approved the marijuana plant as medicine.

However, scientific study of the chemicals in marijuana, called cannabinoids, has led to two FDA-approved medications that contain cannabinoid chemicals in pill form. Continued research may lead to more medications.

Because the marijuana plant contains chemicals that may help treat a range of illnesses and symptoms, many people argue that it should be legal for medical purposes. In fact, a growing number of states have legalized marijuana for medical use.

Why isn’t the marijuana plant an FDA-approved medicine?

The FDA requires carefully conducted studies (clinical trials) in hundreds to thousands of human subjects to determine the benefits and risks of a possible medication. So far, researchers haven't conducted enough large-scale clinical trials that show that the benefits of the marijuana plant (as opposed to its cannabinoid ingredients) outweigh its risks in patients it's meant to treat.

"The historical development of research on cannabidiol".

"The aim of this review is to describe the historical development of research on cannabidiol". (Department of Neurology, Psychiatry and Medical Psychology, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (USP), Ribeirão Preto (SP), Brazil)

After the elucidation of the chemical structure of cannabidiol in 1963, the initial studies showed that cannabidiol was unable to mimic the effects of Cannabis. In the 1970's the number of publications on cannabidiol reached a first peak, having the research focused mainly on the interaction with THC and its antiepileptic and sedative effects. 

The following two decades showed lower degree of interest, and the potential therapeutic properties of cannabidiol investigated were mainly the anxiolytic, antipsychotic and on motor diseases effects. 

The last five years have shown a remarkable increase in publications on cannabidiol mainly stimulated by the discovery of its anti-inflammatory, anti-oxidative and neuroprotective effects. These studies have suggested a wide range of possible therapeutic effects of cannabidiol on several conditions, including Parkinson's disease, Alzheimer's disease, cerebral ischemia, diabetes, rheumatoid arthritis, other inflammatory diseases, nausea and cancer. 

CANNABIDIOL (CBD) Pre-Review Report by WHO

This report has been drafted under the responsibility of 

the WHO Secretariat, Department of Essential Medicines and Health Products, Teams of Innovation, Access and Use and Policy, Governance and Knowledge

(Expert Committee on Drug Dependence. Thirty-ninth Meeting Geneva, 6-10 November 2017)

Summary:

Cannabidiol (CBD) is one of the naturally occurring cannabinoids found in cannabis plants. It is a 21-carbon terpenophenolic compound which is formed following decarboxylation from a cannabidiolic acid precursor, although it can also be produced synthetically, CBD can be converted to tetrahydrocannabinol (THC) under experimental conditions, however, this does not appear to occur to any significant effect in patients undergoing CBD treatment. 

In experimental models of abuse liability, CBD appears to have little effect on conditioned place preference or intracranial self-stimulation. In an animal drug discrimination model CBD failed to substitute for THC. In humans, CBD exhibits no effects indicative of any abuse or dependence potential. There is unsanctioned medical use of CBD based products with oils, supplements, gums, and high concentration extracts available online for the treatment of many ailments.

CBD is generally well tolerated with a good safety profile. Reported adverse effects may be as a result of drug-drug interactions between CBD and patients’ existing medications. Several countries have modified their national controls to accommodate CBD as a medicinal product. To date, there is no evidence of recreational use of CBD or any public health related problems associated with the use of pure CBD.

"3 Cannabinoids In Clinical Practice"

Acording to the study,"Cannabis has a potential for clinical use often obscured by unreliable and purely anecdotal reports".

The most important natural cannabinoid is the psychoactive Tetrahydrocannabinol (A 9 -THC),Cannabidiol (CBD) and Cannabigerol (CBG). Not all the observed effects can be ascribed to THC, and the other constituents may also modulate its action. For example CBD reduces anxiety induced by THC. A standardised extract of the herb may be therefore be more beneficial in practice and clinical trial protocols have been drawn up to assess this. 

The mechanism of action is still not fully understood, although can- nabinoid receptors have been cloned and natural ligands identified. 

Medical Marijuana Faces Acceptance Barrier by Hesitant Medical Schools

A new study shows a growing interest by university pharmacy programs in teaching about medical marijuana in their curriculum, while medical schools seem to lag behind. 62% of US pharmacy school respondents queried in a new survey said they included medical marijuana in their doctorate of pharmacy curriculum.

That’s according to a nine-page study co-authored by faculty from the University of Pittsburgh School of Pharmacy, which appeared in the January 2019 issue of the journal Currents in Pharmacy Teaching and Learning. The results point to the growing role of marijuana as a therapeutic treatment.

The Global Hemp Marketplace

Farm Bill 2018 special reports that "Roughly 30 countries in Asia, Europe, and North and South America already allow hemp cultivation".

The United Nations’ Food and Agriculture Organiszation, which tracks global farming, reports that "Global acreage in hemp cultivation in 2016—the most recent year available—was 192,000 acres. The U.N. estimated total hemp production in 2016 at 355 million pounds".
But those numbers are incomplete.Not all nations report hemp acreage to the U.N. 

 Among the producers left out of the U.N.’s hemp count: 
• Canada, where industry groups say about 138,000 acres of hemp were planted in 2018.
• Uruguay, where 2,471 acres of hemp were licensed in 2018.
• Colombia, where acreage counts are not available. With those exceptions, global acreage in hemp cultivation in 2016 was 192,000 acres, with total production of 355 million pounds. Leading hemp producers are:
• *European Union
• China
• South Korea
• Russia
(*Most production takes place in France, the Netherlands, Lithuania and Romania.) Many of the Latin American countries that have been developing cannabis legislation have been cautious to allow cultivation and started with restrictive, import-only programs of CBD products—which opens the door for new hemp producers to enter the market.
These include:
• Brazil
• Argentina
• Paraguay
• Mexico
But legislation is evolving rapidly, and only Brazil has no plans in place to eventually allow cultivation.

Global investment 

The Farm Bill is certain to trigger a global shift in cannabis investing. That’s because U.S.-based hemp companies now have full access to the largest and most prestigious exchanges, Nasdaq and the New York Stock Exchange. Will Wall Street create hemp giants that will leverage their capital and competitive edge overseas? According to Preston Gardner, an analyst with CVC Partners, U.S. hemp investors should expect:
• Significant M&A activity.
• Hemp activity in the agricultural, pharmaceutical and technology industries.
• American hemp companies seeking a global edge through quality control. 

The last point could be the best way for U.S. hemp entrepreneurs to compete against larger hemp producers around the globe. “Our cost to cultivate is going to be greater compared with international competitors,” Gardner said. He believes American hemp producers will tout “a quality differentiation factor,” particularly their expertise cultivating high-CBD cultivars. 

Instituting quality considerations, such as Good Manufacturing Practice and standard operating procedures, will be key for American hemp to find markets overseas. 
For Free download the Farm Bill 2018 Special Report :
https://hempindustrydaily.com

World Health Organization Recommends Reclassifying Marijuana Under International Treaties

Global health experts at the United Nations are recommending that marijuana and its key components be formally rescheduled under international drug treaties.

The World Health Organization (WHO) is calling for whole-plant marijuana, as well as cannabis resin, to be removed from Schedule IV—the most restrictive category of a 1961 drug convention signed by countries from around the world.

Cannabis Oil In Israeli Autism Study Has 90% Success Rate!

Israeli medical cannabis firm, Tikun Olam, has completed autism clinical trial with CBD-rich Avidekel cannabis oil. The results are very hopeful for autism patients.

Media images of sick children taking cannabis oil brought medical cannabis to the mainstream. Often, the most extreme cases made the biggest impacts—Charlotte Figi, Alyssa Erwin, Haleigh Cox. While most families will never endure the trials of caring for a child with Dravet syndrome, brain cancer, or cerebral palsy, one condition could hit close to home: autism. Fortunately, the Avidekel chemovar by Tikun Olam is proven effective in treating symptoms of autism in recent clinical trial.

How Monsanto shuts down your kidneys, liver, brain, and immune system

A recently released “state of the science” review by the Pesticide Action Network International (PAN) contains a wealth of research that documents the adverse environmental and human health impacts of glyphosate and glyphosate-based herbicides.  The review’s findings emphasize the need for these compounds to be permanently phased out.

Health and environmental advocates say the monopoly on what has become the world’s most-used herbicide – which is the primary ingredient in Monsanto’s Roundup – ought to be a wake-up call for governments, regulatory agencies and farmers around the world who use it.

Chemotherapy Side Effects: Cannabinoids and CBD Research Overview

Chemotherapy can cause several, sometimes debilitating, side effects. Studies have shown cannabinoids can make the adverse effects more manageable.

Chemotherapy is a category of cancer treatment that uses strong drugs, administered orally or intravenously.

There are more than 100 chemotherapy drugs that are used in the treatment of cancer. The drugs prevent cancer from spreading to other parts of the body, slow the growth of tumors, and kill cancer cells.




While chemotherapy can be effective against cancer, it does cause sometimes-serious side effects.

Overview of Chemotherapy Side Effects

The side effects from chemotherapy develop because the chemotherapy drugs that attack cancerous cells also damage normal, healthy cells. Common side effects associated with chemotherapy are fever and chills, fatigue, nausea and vomiting, sore mouth, diarrhea, constipation, loss of appetite that can lead to anorexia, pain or difficulty with swallowing, swelling in the hands or feet, itching, shortness of breath, cough, and muscle or joint pain.

Individuals undergoing chemotherapy won’t necessarily experience all side effects and the severity of the side effects varies greatly from person to person. Most side effects will gradually go away after completion of the treatment.

Effects of Cannabinoids and CBD on Chemotherapy Side Effects

Cannabinoids have shown to effectively reduce the nausea and vomiting that often occurs during and after chemotherapy treatments. Studies have found that one of the major cannabinoids found in cannabis, cannabidiol (CBD), is effective at treating the more difficult to control symptoms of nausea, as well as preventing anticipatory nausea in chemotherapy patients. Another study found that tetrahydrocannabinol (THC), another major cannabinoid found in cannabis, is also effective at reducing conditioned rejection and chemotherapy-induced nausea.