Article History: This study was received on 26 December 1974, accepted on
30 May 1975 and published on 01 September 1975 in the JNCI
(Journal of the National Cancer Institute),Volume 55, Issue 3, Pages 597–602, https://doi.org/10.1093/jnci/55.3.597
The Summary Of The Study...
Lewis lung adenocarcrnoma growth was retarded by the oral administration of Δ9-THC, Δ8-THC, and CBN, but not CBD.
Animals treated for 10 consecutive days with Δ9-THC, beginning the day after tumor implantation, demonstrated a dose-dependent action of retarded tumor growth.
-Mice treated for 20 consecutive days with Δ8-THC and CBN had reduced primary tumor size.
-CBD showed no inhibitory effect on tumor growth at 14, 21, or 28 days.
-Δ9-THC, Δ8-THC, and CBN increased the mean survival time 36% at 100 mg/kg, 25% at 200 mg/kg, and 27% at 50 mg/kg, respectively, whereas CBD did not.
-Δ9-THC administered orally daily until death in doses of 50, 100, or 200 mg/kg did not increase the life-spans of mice hosting the murine leukemia.
However, Δ9-THC administered daily for 10 days significantly inhibited Friend leukemia virus-induced splenomegaly by 71% at 200 mg/kg as compared to 90.2% for actinomycin D.
Experiments with bone marrow and isolated Lewis lung cells incubated in vitro with Δ9-THC and Δ8-THC showed a dose-dependent inhibition 80–20%, respectively, of tritiated thymidine and14C-uridine uptake into these cells.
CBD was active only in high concentrations.
so....
As we all can understand, we dont have to do with a plant whose magical /medical benefits appeared suddenly in our lives but with a plant that is known for decades for the medical uses and in "modern life"... if you search at internet, you will find that from ancient years until today the researchers always discover something new about the benefits of Cannabis...
So the next logical thought is, who and why they try to stay, all these studies, in the "back stage" of the knowlege...
Source: https://academic.oup.com
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