"Study Appears the Bennefits of CBD To Healthy Volunteers & Epileptic Patients"

Anecdotal reports on the antiepileptic properties of marihuana (Cannabis sativa) are known since ancient times. Rosenthal in 1971 mentioned medieval Arab manuscripts in which cannabis is describedas a treatment for epilepsy, as diuretic, anti-emetic, anti-epileptic, antiinflammatory, painkilling and antipyretic properties, among others. During the 19th century several medical reports were published on the ameliorative effects of cannabis extracts on several forms of convulsions.

In spite of promising results and its low toxicity,the use of cannabis preparations for medical purposes progressively decreased.  This was due to the absence of standardized preparations, the unknown chemical composition, and the psychotropic secondary effects produced by cannabis. 

This study supported from the US National Institutes of Mental Health and published on acsalaska.net.


-For the 1st experiment 15 patients suffering from secondary generalized epilepsy with temporal focus were randomly divided into two groups. Each patient received, in a double-blind procedure, 200-300 mg daily of CBD or placebo.The  experiment concluded that :

"All patients and volunteers tolerated CBD very well and no signs of toxicity or serious side effects were detected on examination.4 of the 8 CBD subjects remained almost free of convulsive crises" 

3 other patients demonstrated partial improvement in their clinical condition. CBD was ineffective in 1 patient. The clinical condition of 7 placebo patients remained unchanged whereas the condition of 1 patient clearly improved.

-For the 2nd experiment,16 good health adult volunteers aged 22-35, were chosen from the staff of Escola Paulista de Medicina and performed in the Neurology Out-Patient Clinics of the Hospital Sao Paulo and the Hospital da Santa Case.This experiment concluded that : 

"none of the  patients receiving CBD showed evidence of behavioral alterations which could be suggestive of a psychotropic effect.CBD did not induce any psychic or other side effects and was well tolerated. CBD does not appear to have any toxic effect in humans when administered at the above dosage over a long period."

The summaryof this work is that according to the present data, 

"CBD may turn out to be a useful drug for the treatment of some cases of epilepsy and there is hardly any toxicity." 

CBD had a beneficial effect in patients suffering from secondary generalized epilepsy with temporal foci, who did not benefit from know anti-epileptic drugs. Further research with more patients and other forms of epilepsy is needed to establish the scope of the antiepileptic effects of CBD in humans.

Treatment of epilepsy is based mainly on anticonvulsant drugs. 

However, even when properly administered in well-diagnosed cases, these
drugs succeed in helping only about 70-75% of the epileptic patients but the 30% of the patients do not benefit at all and all clinically effective antiepileptic drugs induce undesirable side effects at normal dosage