Cannabidiol (CBD), the major non-psychoactive constituent of Cannabis sativa, has received attention for therapeutic potential in treating neurologic and psychiatric disorders.
Recently, CBD has also been explored for potential in treating drug addiction.
Substance use disorders are chronically relapsing conditions and relapse risk persists for multiple reasons including craving induced by drug contexts, susceptibility to stress, elevated anxiety, and impaired impulse control. This study from NCBI was published online in 2018 Mar 22 and evaluate the “anti-relapse” potential of CBD in animal models of drug seeking, anxiety and impulsivity.
The Study...
For the study, rats with alcohol or cocaine self-administration histories received transdermal CBD at 24 h intervals for 7 days and were tested for context and stress-induced reinstatement, as well as experimental anxiety on the elevated plus maze.
Recently, CBD has also been explored for potential in treating drug addiction.
Substance use disorders are chronically relapsing conditions and relapse risk persists for multiple reasons including craving induced by drug contexts, susceptibility to stress, elevated anxiety, and impaired impulse control. This study from NCBI was published online in 2018 Mar 22 and evaluate the “anti-relapse” potential of CBD in animal models of drug seeking, anxiety and impulsivity.
The Study...
For the study, rats with alcohol or cocaine self-administration histories received transdermal CBD at 24 h intervals for 7 days and were tested for context and stress-induced reinstatement, as well as experimental anxiety on the elevated plus maze.