"Can CBD help With Neuroinflammation"

Neuroinflammation is an inflammatory condition of the brain, in which glial cells,namely,astrocytes 
and microglia,the resident macrophages of the brain, are involved along with blood-borne cells. 

Although in the past glial activation in neuroinflammation has been considered detrimental to the brain in general, currently the reparative/ protective aspects are being recognized. 

Cannabinoids, whether plant derived or endogenous  affect different glial functions. 

Importantly, glial cells are endowed with several, if not all, of the elements of the endocannabinoid system, and therefore are sensitive to cannabinoids and at the same time are a source of endocannabinoids. 

There appears to be general agreement that cannabinoids reduce the synthesis, production, and release of cytotoxic molecules such as proinflammatory cytokines and nitric oxide. 

On the other hand, these agents modify microglial cell migration in such a way that the result is usually beneficial in resolving neuroinflammation or limiting ensuing neurodegeneration.

"University of Guelph Researchers Unlock Access to Pain Relief Potential of Cannabis"

Researchers of the University of Guelph are the first to uncover how the cannabis plant creates important pain-relieving molecules that are 30 times more powerful at reducing inflammation than Aspirin.
Tuesday, July 23, 2019


The discovery unlocks the potential to create a naturally derived pain treatment that would offer potent relief without the risk of addiction of other painkillers.

“There’s clearly a need to develop alternatives for relief of acute and chronic pain that go beyond opioids,” said Prof. Tariq Akhtar, Department of Molecular and Cellular Biology, who worked on the study with MCB professor Steven Rothstein. “These molecules are non-psychoactive and they target the inflammation at the source, making them ideal painkillers.”

Using a combination of biochemistry and genomics, the researchers were able to determine how cannabis makes two important molecules called cannflavin A and cannflavin B.

"CBD is a Powerful New Antibiotic"

New research published by the American Society for Microbiology has found that CBD is active against Gram-positive bacteria, including those responsible for many serious infections (such as Staphylococcus aureus and Streptococcus pneumoniae), with potency similar to that of established antibiotics such as vancomycin or daptomycin.

The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology.

The project was co-funded by Botanix and Innovation Connections, an Australian government grant scheme to commercialize new products, processes and services. The paper will be presented on Sunday June 23rd from 11am-1 pm at the annual conference of the American Society for Microbiology, ASM Microbe 2019, at the Moscone Convention Center in San Francisco.

CBD, the main non-psychoactive chemical compound extracted from cannabis and hemp plants, has been approved by FDA for the treatment of a form of epilepsy, and is being investigated for a number of other medical conditions, including, anxiety, pain and inflammation. While there is limited data to suggest Cannabidiol can kill bacteria, the drug has not been thoroughly investigated for its potential as an antibiotic.

Work led by Dr Mark Blaskovich at The University of Queensland’s Institute for Molecular Bioscience’s Centre for Superbug Solutions, in collaboration with Botanix Pharmaceuticals Ltd, an early stage drug discovery company investigating topical uses of synthetic cannabidiol for a range of skin conditions, found that "Cannabidiol was remarkably effective at killing a wide range of Gram-positive bacteria, including bacteria that have become resistant to other antibiotics, and did not lose effectiveness after extended treatment."

“Given cannabidiol’s documented anti-inflammatory effects, existing safety data in humans, and potential for varied delivery routes, it is a promising new antibiotic worth further investigation,” said Dr. Blaskovich.

“The combination of inherent antimicrobial activity and potential to reduce damage caused by the inflammatory response to infections is particularly attractive.”

Importantly, the drug retained its activity against bacteria that have become highly resistant to other common antibiotics. Under extended exposure conditions that lead to resistance against vancomycin or daptomycin, Cannabidiol did not lose effectiveness.Cannabidiol was also effective at disrupting biofilms, a physical form of bacteria growth that leads to difficult-to-treat infections.

Source: American Society for Microbiology

"5 Ways CBD Can Improve Your Digestive System" by CBDfx

By now, many of us are aware of the fact that CBD has an abundance of health properties that benefit the body and mind. 

This amazing plant-based compound is renowned for its positive effects on sleep, mood, and pain.

One of the lesser known benefits of CBD is its amazing ability to improve the digestive system.  It seems that CBD is capable of treating an enormous range of ailments that can affect the digestive tract.  From nausea to irritable bowel disease, hemp seems to be able to do it all.

If you suffer from a digestive ailment, this article is for you.  We’re going to delve into how CBD interacts with your digestive system so you can fully understand this plant-based compound and its unique ability to address underlying issues and alleviate symptoms.

-How The Digestive System Works

The digestive system is responsible for taking in food in order to turn it into nutrients that help maintain the body’s overall health.  What the body doesn’t need is turned into waste that exits the body.

The digestive tract runs along the body, starting at the mouth and ending at the anus.  Many people don’t realize just how much energy their body uses in order to digest food on a daily basis.  Many organs play a role in digestion, helping to break down nutrients and enzymes while passing food through the body.

Because of how crucial the digestive system is to a person’s overall health, a digestive disease or disorder can result in serious health-related consequences.  Because of how enormous the digestive system is, there is a huge variety of ailments that can occur along the digestive tract.

Recent studies on digestive system issues suggest that our mood can be greatly affected by the state of our digestive tract.  Now, medical researchers believe that dietary and digestive issues can result in mood disorders such as anxiety and depression.

-Medication for the Digestive System

With so many different types of digestive ailments out there, there are countless medications that a person can take in order to improve their digestive system.  The problem is that many medications are known for their side effects.

If you wish to treat your digestive issues naturally, it might be time to look into CBD.  This plant-based compound has the unique ability to supply the body with what it needs in order to address the underlying cause of the ailment.  Plus, it’s widely considered to be safe and non-addictive.

-Is CBD Good for the Digestive System?

Thanks to an abundance of recent studies, medical researchers believe that CBD benefits the digestive system in many ways.  Because of its anti-inflammatory properties, CBD can relieve inflammation along the digestive tract.  Many health experts believe that chronic inflammation is the leading cause of several different chronic digestive issues such as colitis, irritable bowel disease, and leaky gut syndrome.

Also, the digestive tract has CB1 and CB2 receptors.  These receptors interact with cannabinoids in order to produce chemical reactions that result in healing.  The body has an endocannabinoid system that should be able to produce cannabinoids on its own.  However, many of us are deficient in cannabinoids due to a variety of factors.  CBD helps supply the body with the cannabinoids that it needs in order to keep the digestive system running smoothly.

-CBD and Your Stomach

If you wish to take CBD for the digestive system, you can rest assured that this plant-based compound is very easy on the stomach.  While many herbs and other natural medicines can cause stomach cramps and painful gas, cannabis has a soothing effect on the entire digestive tract.

1-Relief from Symptoms of Inflammatory Digestive Disorders

CBD is a powerful anti-inflammatory, meaning it can dramatically reduce inflammation throughout the body.  When consumed, it can reduce swelling and pain that exists along the digestive tract.  If you suffer from an inflammatory disease like irritable bowel syndrome, CBD might be able to help on a profound level.

CBD lowers inflammation by improving the immune system’s response to what it perceives as an injury or threat.  It attaches itself to CB1 and CB2 receptors along the digestive tract in order to boost the functionality of the area while lowering the amount of white blood cells that are in the area.

2-Relief from Nausea, Vomiting, and Poor Appetite

CBD is a powerful anti-nausea agent that can decrease instances of vomiting while improving one’s appetite.  It acts as an antispasmodic, reducing the number of spasms along the digestive tract that can make a person feel nauseous.  It has a calming effect on the esophagus, lowering the chances of vomiting after consuming food.

3-Relief from Painful Gas

Because CBD has a calming effect on the digestive tract, it can reduce discomfort caused by excessive gas.  This means that CBD is also capable of lowering bloating along the intestinal tract.

4-Relief from Stress

By now, most of us are aware of the connection between chronic stress and digestive discomfort.  If you suffer from chronic stress or anxiety, your body is producing a lot of cortisol, a hormone that can cause a host of digestive ailments if secreted in large amounts.

CBD is known for its ability to lower cortisol levels, resulting in a calmer mind.  If stress is giving you digestive troubles, reach for CBD in order to enjoy its cortisol-busting effects.

5-Relief from General Pain

CBD has an impressively high level of analgesic activity, meaning that it can lower pain quickly and effectively by blocking the brain’s ability to receive pain signals from the nervous system.  If you’re dealing with severe pain along the digestive tract, CBD can provide you with the relief that you deserve.

-How to Take CBD for Your Digestive System

Before you purchase any old CBD product that you come across, it’s crucial that you do some research in order to fully grasp the range of products that are out there.  We also suggest that you speak to a doctor before treating your digestive issues with CBD.

Many people are confused when it comes to how much CBD they should take in order to address their unique symptoms.  The good news is that CBD is nontoxic, meaning that you can feel free to play around with your dose.  However, taking too much CBD at once can make you feel sleepy.  Therefore, try taking it before bedtime in order to monitor its effects.

It’s also important to keep in mind that CBD will not make you feel high.  It comes from the hemp plant, a member of the cannabis family.  Marijuana also belongs to the cannabis family.  However, unlike marijuana, hemp does not possess any psychoactive activity.

CBD Products for the Digestive System

-CBD Gummies with Turmeric & Spirulina

The CBD Gummies with Turmeric & Spirulina are extremely popular among those who wish to treat their digestive issues with hemp.  These gummy candies taste great and are packed with nutrients that your body needs.  In addition to gut-healing CBD, these gummies have turmeric, a potent anti-inflammatory that can soothe the digestive tract quickly and effectively.  Plus, they’re made with only plant-based ingredients.

-CBD Hemp Capsules

The CBD Hemp Capsules can be taken daily with or without food.  They’re made with only plant-based ingredients and won’t irritate your stomach.  These capsules are excellent for those who have digestive issues because of the way in which they move through the digestive tract, providing relief every step along the way.

The Benefits Are Evident for an Upset Stomach

The next time your stomach is feeling upset, reach for some high-quality CBD.  This natural compound has what it takes to leave you feeling your very best.

Source:https://cbdfx.com

"CBD & Asthma"

Asthma is a condition in which your airways narrow and swell and produce extra mucus. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

For some people, it can be a major problem that interferes with daily activities and may lead to a life-threatening asthma attack.

Asthma can't be cured, but its symptoms can be controlled. Because asthma often changes over time, it's important that you work with your doctor to track your signs and symptoms and adjust treatment as needed so lets see how can CBD help with asthma 

-4 Studies About CBD & Asthma

-Ιn 2015 the Department of Neurosciences of the University of São Paulo and the Laboratory of Experimental Physiopathology they studied the role of CBD Treatment in Animal Model of Asthma.

Researchers found that the treatment with CBD in a model of acute lung injury induced by lipopolysaccharide (LPS) decreased total lung resistance and elastance and improved several markers of inflammation. The protective effects of CBD upon lung inflammation were demonstrated in several different models.